As we age, hormone levels often
decline or become imbalanced. Especially
past the age of 35 years, hormonal imbalances begin to show up. Many times these imbalances can be corrected by restoring
hormone levels to youthful optimal levels.
Often progesterone replacement
therapy is given to women, especially in combination with estrogen replacement
therapies. There are different
forms of progesterone replacement therapy, mainly oral and transdermal (creams).
The liver metabolizes progesterone
to several compounds. Therefore,
when you orally use progesterone, it will pass through the liver, before it
reaches the bloodstream. The liver
will metabolize it, making it ineffective.
One possibility for oral compounds that have progestational activities
are compounds that avoid the liver, (Robert K. Murray, MD, Ph.D., Daryl K.
Granmer, MD, Peter A. Mayes, Ph.D., D.Sc., Victor W. Fodwell, Ph.D., Harper's
Biochemistry, twenty-fifth edition. Appleton
& Lance, Stanford, Connecticut, 2000.)
Therefore, according to the latest
biochemical science, oral progesterone may be ineffective.
Since many cancers are related to estrogen imbalance and excess estrogen,
and since progesterone helps control estrogen levels and imbalance, ineffective
progesterone therapy can result in grave problems.
Thus, women should question oral progesterone prescriptions, and search
for hormone specialists that prescribe creams and other methods of progesterone
therapy besides oral. This can be a
life and death decision.
In conclusion, we advise
progesterone cream in many articles contained on this web site.
The method using transdermal cream, bypasses the liver, and thus it can
enter the bloodstream and be effective.
Note – progesterone
pellets mimic progesterone transdermal cream by entering the bloodstream and
bypassing the liver. However, their
effectiveness in the United States has not yet been proven to result in stable
and appropriate progesterone effects.
– In order for these nutritional ideas to be successful, you must use
supplements of the highest quality. Dr. Bob often said, “almost all supplement
companies produce poor quality.” You
can consider the product page of this web site. Almost
all the products met Dr. Bob’s approval.
Since he passed away we have attempted to keep the same high standards.
WARNING: DO NOT STOP ANY
TREATMENT OR MEDICATION YOU CURRENTLY USE.
CONSULT WITH YOUR DOCTOR BEFORE STARTING THE USE OF SUPPLEMENTS.
The Food and Drug Administration has not evaluated any of
the statements contained on this web site. The information contained in this
article is not intended to diagnose, treat, cure or prevent any disease.
Remember each person's body is different and will react differently to various
herbal, vitamin and mineral supplements. Therefore, any supplementation must be
administered on an individual basis. Use the information found on this web site
as precisely that: Information. You and your doctor must make any final
decisions. This information is not meant to replace any doctor and patient
consultation. This information should in no way replace your personal
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Page Last Updated: 21JAN02